Hypertrophic pulmonary osteoarthropathy

Thickening of the long bones due to hypertrophic pulmonary osteoarthropathy. This animal has obvious locomotion difficulties. Local limb temperature was increased due to inflammation of the skin covering the affected bones. Limb thickening was partially due to subcutaneous oedema. The right-side image shows a large primitive tumour (T) of the lung that was responsible for the hypertrophic pulmonary osteoarthropathy. The small nodules are metastases of the primitive tumour. Below, note the periosteal irregularity and thickening of the humerus, tibia and fibula due to ossifying periostitis.