Osteochondrosarcoma of the submandibular salivary gland

Osteochondrosarcoma of the submandibular salivary gland of a 4-year-old female Cocker Spaniel. The pearl-like millimetric formations of bony consistency that can be seen in the image correspond to foci of infiltration of the salivary gland by neoplastic cells of osseous and cartilaginous origin, arranged in compact spheres separated by a delicate conjunctive stroma with identifiable peripheral areas of trabecular bone. The tumour has completely infiltrated and destroyed the parenchyma of this salivary gland. In spite of the tumour’s unusual architecture, the tumour cells exhibited a high level of differentiation.